About Black Pepper
The King of Spices.
Through-out history, pepper was highly prized for both its culinary and medicinal properties. Black pepper was a well-known and wide spread seasoning dating back to the Roman Empire. Up to the early Middle Ages, peppercorns were a much-prized trade good often referred to as “black gold”, and an item exclusively for the rich. Pepper was so valuable that it was often used as commodity money, collateral or even currency. In the Dutch language, “pepper expensive” (peperduur) is an expression for something very expensive. Black pepper was valued in ancient Egypt and included in the burial ritual of Ramesses II in 1213 BC, and appears in the Buddhist Samaññaphala Sutta, as one of the few medicines a monk is allowed to carry.
Since about 1840’s, the word pepper was used in a figurative sense to mean “spirit” or “energy”. In the 20th century, this was shortened to “pep” , meaning spicy and it wakes you up ie : pep rallies.
Pepper gets its spicy heat mostly from the compound piperine. However it is Beta-Caryophyllene that gives pepper it’s characteristic fragrance and is the focus of international studies and research.
Beta-Caryophyllene is a dietary Cannabinoid and binds to CB2 receptors providing potent pain and anti-inflammatory relieve. This explains why black pepper (Beta-Caryophyllene) commonly appears in many anti-inflammatory preparations. Both ß-Caryophyllene and Humulene demonstrate pronounced neuropathic pain relief and anti-inflammatory properties. Studies indicate the effects are comparable to those observed in dexamethasone-treated lab animals. *
Golden Oasis Plus+ contains a large concentration of Beta-Caryophyllene to maximize this potent benefit.
*These Statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.
Klauke AL, Racz I, Pradier B,Markert A, Zimmer AM, Gertsch J et al. (2014). The cannabinoid CB receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in models of inflammatory and neuropathic pain.
Eur Neuropsychopharmacol 24: 608-620.
Pacher P PhD, Gertsch J, Sharon Anavi-Goffer ; Effects of the dietary natural product beta-caryophyllene in vivo, the role of the cannabinoid CB2 receptor. National Institutes of Health ; Institute of Biochemistry and Molecular Medicine Sci U S A 105: 9099-9104
Chicca A, Caprioglio D, Minassi A, Petrucci V, Appendino G, Taglialatela-Scafati O et al. (2014). Functionalization of β-caryophyllene generates novel pharmacology in the endocannabinoid system. ACS Chem Biol 9: 1499-1507.
Gertsch J, Leonti M, Raduner S, Racz I, (2008). Anti-inflammatory cannabinoids in diet: towards a better understanding of CB(2) receptor action Commun Integr Biol1: 26-28.
Sharma C, Al Kaabi JM, Nurulain SM, Goyal SN, Kamal MA, Ojha S poly pharmacological Properties and Therapeutic Potential of Beta-Caryophyllene: A Dietary Phytocannabinoid of Pharmaceutical Promise; Curr Pharm Des. 2016;22(21):3237-64.
Fidyt K, Fiedorowicz A, Strzadata L, Szumny A.
β-caryophyllene and β-caryophyllene oxide-natural compounds of anticancer and analgesic properties. Cancer Med. 2016;5(10):3007-3017.