Hemp and Hops are distant cousins in the same plant family of Cannabinaceae.
While Hemp produces the phyto-cannabinoids, Hops provides an abundance of highly complementary compounds and Terpenes including Humulene, Myrcene and Caryophyllene. Combined, the purified extracts and therapeutic grade oils from these source plants create a very powerful synergy, enhancing the overall Entourage effect
Did you know, according to the USDA, that there are approx. 175 varieties of Hops ?
We didn’t either. And it took us quite a while to find the Hops variety and 100% pure organic hops oil, that satisfied our near fanatical commitment of sourcing and using only the purest, most potent and balanced products.
The medical and therapeutic potential of humulene is expansive and well-researched. Humulene is a powerful anti-inflammatory and anti-nociceptive (the action of reducing sensitivity to painful stimuli ) properties has been examined in many studies over the years. Humulene is classified as a sesquiterpene, and named after Humulus lupulus, a.k.a. the hops plant.
It is abundant in hops, sage, ginger and ginseng, and is present in their therapeutic-grade essential oils. The use of these oils for healing purposes dates back centuries.
Humulene has a close biogenic relationship with Beta-Caryophyllene, as they amplify and reinforce each other’s anti-inflammatory properties. Studies indicate that alpha-humulene and beta-caryophyllene both demonstrate pronounced neuropathic pain relief and anti-inflammatory properties. Studies indicate the effects are comparable to those observed in dexamethasone-treated lab animals. *
The potential of humulene to be an effective agent against cancerous tumor growth was been well researched, and studies suggest anti-cancer potential may be increased by the presence of both humulene and Beta-caryophyllene. * This however is beyond the scope of our presentation *
Of all the terpenes extracted from Humulus lupulus (hops), the largest monoterpenes fraction is alpha-myrcene. Myrcene synergizes the activities of terpenes and other compounds in a variety of ways.
Myrcene also has shown powerful anti-inflammatory effects and has been thought to enhance the effects of Beta-Caryophyllene. With inflammation underlying numerous diseases, myrcene is the subject of a broad array of current research.
Beta-Caryophyllene: See Black Pepper
*These Statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.
* Alexandre P. Rogerio, EdinÈia L. Andrade, Daniela F.P. Leite, Preventive and therapeutic anti-inflammatory properties of the sesquiterpene a-humulene British Journal of Pharmacology (2009), 158, 1074ñ1087
* Fernandes ES1, Passos GF, Medeiros R; Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene
* Eur J Pharmacol. 2007 Aug 27;569(3):228-36. Epub 2007 May 22.
* Legault J1, Pichette A. Potentiating effect of beta-caryophyllene on anticancer activity of alpha-humulene J Pharm Pharmacol. 2007 Dec;59(12):1643-7
* Nguyen LT, Myslive?kov· Z The inhibitory effects of beta-caryophyllene, beta-caryophyllene oxide and a-humulene Chem Biol Interact. 2017 Dec 25;278:123-128. doi: 10.1016/j.cbi.2017.10.021. Epub 2017 Oct 23.